Delcath Systems, Inc.

1633 Broadway, Suite 22C

New York, NY 10019

August 2, 2018

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street N.E.

Washington, D.C. 20549

 

Attention:

Dan Morris, Esq.

Tim Buchmiller, Esq.

Re:	Delcath Systems, Inc.

Registration Statement on Form S-1

File No. 333-225567

REQUEST FOR ACCELERATION OF EFFECTIVENESS

Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Delcath Systems, Inc. (the “Registrant”) hereby respectfully requests acceleration of the effective date of its Registration Statement on Form S-1 (File No. 333-225567), as amended (the “Registration Statement”), so that it may become effective at 5:00 p.m. Eastern Time on August 3, 2018, or as soon as practicable thereafter.

The Registrant hereby authorizes Jolie Kahn, Esq., to orally modify or withdraw this request for acceleration.

We respectfully request that we be notified of such effectiveness by a telephone call to Ms. Kahn at (516) 222-2230.

Very truly yours,

DELCATH SYSTEMS, INC.

/s/ Barbra Keck

Barbra Keck

Chief Financial Officer